Tom Brady and Randy Moss pulled out of the Pro Bowl on Monday, a day after the New England Patriots were beaten in the Super Bowl.
After throwing a league-record 50 touchdown passes during the season, Brady was battered by the New York Giants during their 17-14 win Sunday. He has been bothered by a tender ankle and was photographed in New York wearing a protective boot two weeks before the Super Bowl.
Brady will be replaced by Cleveland Browns quarterback Derek Anderson.
Moss, who caught a record 23 touchdown passes from Brady during the season, had five receptions for 62 yards and a TD in the Super Bowl. He will be replaced by Cincinnati Bengals receiver Chad Johnson.
The Patriots said Brady and Moss each opted out because of ankle injuries.
San Diego tight end Antonio Gates (toe) and defensive tackle Jamal Williams (ankle) also decided to skip Sunday's all-star game in Honolulu.
Browns tight end Kellen Winslow will go in place of Gates, bringing the number of Browns players in the Pro Bowl to six, the club's most since sending six in 1994. Pittsburgh Steelers defensive tackle Casey Hampton takes Williams' spot on the AFC roster, his third-consecutive trip to Hawaii and fourth overall.
