In 2013, the Patriots will play each of the other AFC East rivals twice and will play one game against each of the AFC North and NFC south teams. As the first-place team in the AFC East, the Patriots will play the first-place teams of the AFC South (Houston) and the AFC West (Denver).
HOME
| TEAM | W | L | Pct. |
| Denver Broncos | 13 | 3 | .813 |
| Pittsburgh Steelers | 8 | 8 | .500 |
| New Orleans Saints | 7 | 9 | .438 |
| Miami Dolphins | 7 | 9 | .438 |
| Tampa Bay Buccaneers | 7 | 9 | .438 |
| New York Jets | 6 | 10 | .375 |
| Buffalo Bills | 6 | 10 | .375 |
| Cleveland Browns | 5 | 11 | .313 |
AWAY
| TEAM | W | L | Pct. |
| Atlanta Falcons | 13 | 3 | .813 |
| Houston Texans | 12 | 4 | .750 |
| Baltimore Ravens | 10 | 6 | .625 |
| Cincinnati Bengals | 10 | 6 | .625 |
| Miami Dolphins | 7 | 9 | .438 |
| Carolina Panthers | 7 | 9 | .438 |
| New York Jets | 6 | 10 | .375 |
| Buffalo Bills | 6 | 10 | .313 |
